Platforms
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2026 AACR | Iterative engineering of GPC-3 targeted synthetic TCR and antigen receptor (STAR) cells in advanced solid tumors
April 21, 2026 Changsong Qi; Jiarui Li; Chang Liu; Hongli Zheng; Dongmei Yang; Dan Liu; Panpan Zhang; Miao Zhang; Ran Xue; Jifang Gong; Lian Liu; Min Tao; Siyuan Cheng; Jian Li; Xiaotian Zhang; Jin Yin; Xueqiang Zhao; Xin Lin; Lin Shen -
2025 Mol Ther | Converting TCR-based chimeric antigen receptor STAR into dual-specific targeting receptor for cancer immunotherapy
February 05, 2025 Li Yu , Zhixiao Zhou , Hanyang Yu , Yue Liu , Daosheng Huang , Jiasheng Wang , Xin Lin -
2025 Nat Med | Allogeneic CD19-targeting T cells for treatment refractory systemic lupus erythematosus: a phase 1 trial.
August 27, 2025 Xiaobing Wang , Yi Zhang , Huimin Wang , Xin Wu , Chao He , Suxian Lin , Kun Pang , Yang Li , Yue Chen , Xiaojing Tang , Xin Liu , Xin Lin , Huji Xu ,etc. -
2024 Cell reports | TCR-mimicking STAR conveys superior sensitivity over CAR in targeting tumors with low-density neoantigens.
August 29, 2025 Daosheng Huang , Yi Li , Wei Rui , Keyong Sun , Zhixiao Zhou , Xiachen Lv , Li Yu , Junfan Chen , Jing Zhou , Vincent Liu , Jiasheng Wang , Xun Lan , Yang-Xin Fu , Xueqiang Zhao , Xin Lin -
2024 ASH | LILRB4 represents a promising target for immunotherapy by dual targeting tumor cells and myeloid-derived suppressive cells in multiple myeloma.
May 30, 2024 Lixin Gong , Hao Sun , Lanting Liu , Xiyue Sun , Teng Fang , Zhen Yu , Weiwei Sui , Jingyu Xu , Tingyu Wang , Fangshuo Feng , Lei Lei , Wei Rui , Yuxuan Liu , Xueqiang Zhao , Gang An , Xin Lin , Lugui Qiu 5, Mu Hao -
2023 AACR | Development of LILRB4 biparatopic synthetic T-cell receptor and antigen receptor (STAR)-T cells for the treatment of acute myeloid leukemia (AML).
May 01, 2023 Wei Rui; Lei Lei; Zezhong Zhang; Chunyan Wu; Yu Xia; Yingying Liu; Xiaojing Pang; Ruifang Du; Lan Wang; Dengyue Sheng; Jing Guo; Yanyan Zhang; Xueqiang Zhao; James Pan -
2022 Am J Hematol | A novel adoptive synthetic TCR and antigen receptor (STAR) T-Cell therapy for B-Cell acute lymphoblastic leukemia.
May 12, 2022 Jiasheng Wang , Xian Zhang , Zhixiao Zhou , Yue Liu , Li Yu , Lemei Jia , Junfang Yang , Jingjing Li Hanyang Yu , Wenzhong Li , Guangna Liu , Wei Rui , Hongli Zheng , Xueqiang Zhao , Xin Lin , Peihua Lu -
2021 EHA | A novel CD19/CD20 dual synthetic T-cell receptor and antigen receptor (STAR) T cell therapy for refractory and relapsed (R/R) B cell acute lymphoblastic leukemia (B-ALL).
June 09, 2021 Junfang Yang, Jiasheng Wang, Xian Zhang, Jingjing Li, Li Yu, Zhixiao Zhou, Lemei Jia, Yue Liu, Hongli Zheng, Xin Lin, Peihua Lu -
2021 ASH | A Novel CMV-Specific TCR-T Cell Therapy Is Effective and Safe for Refractory CMV Infection after Allogeneic Hematopoietic Stem Cell Transplantation.
December 13, 2021 Xingyu Cao , Guangna Liu , Jianping Zhang , Yanli Zhao , Hua Chen , Hongli Zheng , Wei Rui , Lemei Jia , Xueqiang Zhao , Xin Lin , Peihua Lu -
2021 Sci Transl Med | Chimeric STAR receptors using TCR machinery mediate robust responses against solid tumors.
March 21, 2021 Yue Liu , Guangna Liu , Jiasheng Wang , Zhe-Yu Zheng , Lemei Jia , Wei Rui , Daosheng Huang , Zhi-Xiao Zhou , Liqun Zhou , Xin Wu , Song Lin , Xueqiang Zhao , Xin Lin